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Is genotype AC a sickle cell carrier?
Sickle cell anemia refers to an abnormal homozygote genotype (SS or CC), whereas sickle cell trait refers to heterozygote genotype AS or AC inducing mild disease.
Is AC genotype common in Nigeria?
The World Health Organization also reported that an average of 150,000 infants are born with sickle cell disease in Nigeria. The most commonly encountered abnormal hemoglobin genotypes among Nigerians include AS, AC, SC, and SS.
What is d meaning of SC genotype?
The hemoglobin (Hb) SC genotype is seen in persons who have inherited the gene for hemoglobin S from one parent and the gene for hemoglobin C from the other. Some people with this genotype develop Hb SC disease, a variant of sickle cell disease.
Is AC genotype good?
AC is rare, whereas AS and AC are abnormal. The compatible genotypes for marriage are; AA marries an AA — which is the best compatible, and that way, the couple save their future children the worry about genotype compatibility.
What type of blood group is AC?
There are four hemoglobin genotypes (hemoglobin pairs/formations) in humans: AA, AS, SS and AC (uncommon). SS and AC are the abnormal genotypes or the sickle cells. We all have a specific pair of these hemoglobin in our blood which we inherited from both parents.
Is AC a good genotype?
What is AC in sickle cell?
A person who inherits a Hemoglobin A gene from one parent and a Hemoglobin C gene from the other parent, will have Hemoglobin C trait (AC). Approximately one in every 50 black Americans has Hemoglobin C trait. This is not a disease and there are no health problems associated with it.
Is AC better than as genotype?
AC is rare whereas AS and AC are abnormal. Compatible genotypes for marriage are: AA marries an AA. That’s the best compatible.
What is the difference between as and AC genotype?
The genotypes in humans are AA, AS, AC, SS. They refer to the hemoglobin gene constituents on the red blood cells. AC is rare whereas AS and AC are abnormal.
What is the meaning of genotype AC?
AC genotype is an abnormal hemoglobin produced because of the substitution of glutamate with lysine at the 6th position of the second beta-globin chain. People with hemoglobin AC traits are phenotypically normal with no clinical symptoms.
What are the different types of genotypes?
A description of the pair of alleles in our DNA is called the genotype. Since there are three different alleles, there are a total of six different genotypes at the human ABO genetic locus. The different possible genotypes are AA, AO, BB, BO, AB, and OO.
How do you describe a genotype?
Genotypes are the genetic makeups of organisms and are typically referred to with respect to the specific traits they describe. Genotypes exist in the form of genetic data such as DNA or RNA .