What occurs when the rate of bone resorption exceeds the rate of bone formation?

What occurs when the rate of bone resorption exceeds the rate of bone formation?

As people age, the rate of bone resorption far exceeds the rate of bone formation. Thus, bones can weaken, leading to conditions like osteoporosis. Osteoporosis can be prevented with lifestyle changes such as proper nutrition and exercise. The risks of osteoporosis can also be reduced through the prevention of falls.

What disease occurs when bone loss exceeds bone formation?

Osteoporosis occurs when too much bone mass is lost and changes occur in the structure of bone tissue. Certain risk factors may lead to the development of osteoporosis or can increase the likelihood that you will develop the disease.

Does bone formation exceeds bone resorption in osteoporosis?

Bone is a living tissue that is repeatedly broken down (bone resorption) and remade (bone formation) little by little every day. If this balance collapses and bone resorption exceeds bone formation, bone density decreases and can lead to osteoporosis.

When does bone resorption occur?

Bone resorption is resorption of bone tissue, that is, the process by which osteoclasts break down the tissue in bones and release the minerals, resulting in a transfer of calcium from bone tissue to the blood….

Why does bone resorption occur?

During childhood, bone formation exceeds resorption. As the aging process occurs, resorption exceeds formation. Bone resorption rates are much higher in post-menopausal older women due to estrogen deficiency related with menopause….

What causes increased bone resorption?

Clinical disorders in which bone resorption is increased are very common and include Paget’s disease of bone, osteoporosis, and the bone changes secondary to cancer, such as occur in myeloma and metastases from breast cancer.

Which bone disorder is characterized by excessive and haphazard bone deposit and resorption?

Paget disease is a localized disorder of bone remodeling that typically begins with excessive bone resorption followed by an increase in bone formation.

What is bone resorption disease?

Disorders of bone resorption Osteolysis refers to the condition of the bones becoming thin and weak. Some of the common risk factors involved in osteolysis are bone growth such as cysts, joint prosthetics which are materials used for joint replacements and infections that can create the bone loss.

What determines the rate of bone formation and resorption?

The formation and resorption of boneoccur constantly at rates determined by the relative activity of osteoblasts and os-teoclasts. Body growth during the first two decades of life occurs because bone formation proceeds at a faster rate than bone resorption.

What is the pathophysiology of osteoporosis?

Histologically, osteoporosis is characterized by a reduction in the thickness of compact bone and the number and size of trabeculae in cancellous bone. Figure 6.6.2 shows that women lose bone mass more quickly than men starting at about 50 years of age.

What is the difference between Paget’s disease and osteoporosis?

Osteoporosis is a disease characterized by a decrease in bone mass that occurs when the rate of bone resorption exceeds the rate of bone formation, a common occurrence as the body ages. Notice how this is different from Paget’s disease.