Admin Table of Contents
What labs do you monitor with diuretics?
Lab Test Considerations: Monitor electrolytes (especially potassium), blood glucose, BUN, and serum uric acid levels before and periodically throughout course of therapy.
What lab tests should be done routinely for patients taking furosemide?
Lab Test Considerations: Monitor electrolytes, renal and hepatic function, serum glucose, and uric acid levels before and periodically throughout therapy. Commonly ↓ serum potassium.
What lab tests should be done for hypertension?
These lab tests include urinalysis, blood cell count, blood chemistry (potassium, sodium, creatinine, fasting glucose, total cholesterol and HDL cholesterol), and an ECG (electrocardiogram).
Why do diuretics cause hypokalemia?
Because loop and thiazide diuretics increase sodium delivery to the distal segment of the distal tubule, this increases potassium loss (potentially causing hypokalemia) because the increase in distal tubular sodium concentration stimulates the aldosterone-sensitive sodium pump to increase sodium reabsorption in …
How do you monitor diuretic therapy?
Monitoring diuretics
- Re-check blood pressure, renal function and electrolytes within 4-6 weeks of commencing therapy.
- If blood pressure is not adequately controlled by a low dose of thiazide, an additional antihypertensive agent should be considered rather than increasing the dose.
What electrolytes monitor with diuretics?
People with heart failure should have their electrolytes and creatinine assessed before initiation of diuretics and then at one week. Creatinine and electrolytes can be monitored annually in lower risk patients but up to every three to six months in higher risk patients (see box 1).
Is furosemide a thiazide diuretic?
Lasix and thiazides are different types of diuretics. Lasix is a type of “loop” diuretic while thiazides refer to a class of diuretics. Lasix is a brand name for furosemide. Examples of thiazide diuretics include chlorthalidone (Thalitone), hydrochlorothiazide (Microzide), and methyclothiazide.
What labs should be monitor with lisinopril?
Monitor serum potassium, blood pressure, and blood urea nitrogen/serum creatinine in patients taking lisinopril after 2 to 3 weeks of initiation.
What is a thiazide diuretic drug?
Thiazide diuretics are an FDA-approved class of drugs that inhibit the reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. By doing so, thiazide diuretics promote natriuresis and diuresis.
What is more important systolic or diastolic?
Over the years, research has found that both numbers are equally important in monitoring heart health. However, most studies show a greater risk of stroke and heart disease related to higher systolic pressures compared with elevated diastolic pressures.
What electrolyte abnormalities commonly occur with thiazide diuretics?
The main adverse effects of thiazides include hyponatremia, hypokalemia, hypomagnesemia, and hypercalcemia. Thiazide-induced hyponatremia is an often underestimated risk that requires proactive management by clinicians and patients.
How do thiazide diuretics cause hypercalcemia?
Hypercalcemia. By increasing calcium reabsorption from the luminal membrane into the interstitium in exchange for sodium, thiazides reduce urine calcium levels and increase blood calcium.
Why do we monitor patients taking diuretics and what do they monitor?
Why do we monitor patients taking diuretics and what do we monitor? Monitoring a person on diuretics is necessary to assess response to treatment and to prevent adverse events, particularly electrolyte imbalances and decline in renal function (see Tables 1 and 2).
How often should electrolytes be checked after taking diuretics?
People with hypertension taking diuretics should have their electrolytes assessed within four to six weeks of initiating therapy and thereafter can be assessed every six to twelve months unless their clinical condition changes or a potentially interacting drug is added (Table 3).
Are diuretics associated with decline in EGFR?
The use of diuretics was significantly associated with decline in eGFR. A total of 36 (11.5%) patients initiated renal replacement therapy (RRT) and need of RRT was more profound among diuretic users.
What are the different types of diuretics?
General Use. Groups commonly used are thiazide diuretics and thiazide-like diuretics (chlorothiazide, chlorthalidone, hydrochlorothiazide, indapamide, and metolazone), loop diuretics (bumetanide, furosemide, and torsemide), potassium-sparing diuretics (amiloride, spironolactone, and triamterene), and osmotic diuretics (mannitol).