Guidelines

What is Totect used for?

What is Totect used for?

Dexrazoxane injection (Totect, Zinecard) is used to prevent or decrease thickening of the heart muscles caused by doxorubicin in women who are taking the medication to treat breast cancer that has spread to other parts of the body.

Is dexrazoxane a chemo drug?

Doxorubicin forms free radicals which can be harmful to your heart if you are exposed to high enough doses of doxorubicin, Dexrazoxane, a chemoprotectant, is thought to bind to the free radicals formed by doxorubicin limiting their harmful effects and protecting your heart.

What are the side effects of doxorubicin?

Side Effects

  • Cough or hoarseness accompanied by fever or chills.
  • darkening or redness of the skin (if you recently had radiation treatment)
  • fast or irregular heartbeat.
  • fever or chills.
  • joint pain.
  • lower back or side pain accompanied by fever or chills.
  • pain at the injection site.

What cancer is Adriamycin used for?

Adriamycin is a type of chemotherapy, which is used in combination with other chemotherapy medications to treat breast cancer. It can also be used to treat other cancers, such as ovarian cancer, sarcoma, and neuroblastoma. Side effects of Adriamycin include nausea, vomiting, hair loss, mouth sores, and fatigue.

What is anthracycline based chemotherapy?

Anthracyclines is a class of drugs used in cancer chemotherapy that are extracted from Streptomyces bacterium. These compounds are used to treat many cancers, including leukemias, lymphomas, breast, stomach, uterine, ovarian, bladder cancer, and lung cancers.

How long does Emend stay in your system?

This effect can last for up to 28 days after your last dose of this medication. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking aprepitant and for at least 1 month after your treatment ends.

Is dexrazoxane FDA approved?

Clinigen’s Totect® (dexrazoxane) receives FDA approval for new indication to treat incidence and severity of cardiomyopathy associated with doxorubicin in women with metastatic breast cancer.

When is dexrazoxane used?

Dexrazoxane is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications. The Totect brand of dexrazoxane is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun).

Do you lose your hair with doxorubicin?

v Hair loss is unusual with liposomal doxorubicin, but some patients do experience more hair loss than others. If hair loss occurs, hair growth should return upon completion of treatment.

What are side effects of Adriamycin?

Common side effects of Adriamycin PFS (doxorubicin hydrochloride) include:

  • nausea and vomiting (may be severe),
  • diarrhea,
  • loss of appetite,
  • missed menstrual periods,
  • darkening of your skin or nails,
  • weakness,
  • tiredness,
  • eye redness, or.

What are the long-term side effects of Adriamycin?

Long-term gastrointestinal side effects that have been reported with Adriamycin include:

  • Gastric ulcers or erosions.
  • Hyperpigmentation of the tongue or oral mucosa (rare)
  • Ulceration and necrosis of the colon, especially the cecum (rare).

What is Totect used to treat?

Totect (dexrazoxane) is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications. Totect is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun). Extravasation happens when an injected medicine escapes from the blood vessels and circulates into tissues in the body.

How do you administer Totect?

Totect is given as an infusion into a vein. A healthcare provider will give you this injection. Totect is usually started within 6 hours after extravasation, and continued once daily for 3 days. -Product must be diluted with 50 mL of 0.167 M sodium lactate injection solution prior to administration.

What are the side effects of Totect?

Totect side effects. Get emergency medical help if you have signs of an allergic reaction to Totect: hives; difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: fever, chills, tiredness, mouth sores, skin sores; easy bruising, unusual bleeding;

What is Totect (dexrazoxane)?

What is Totect? Totect ( dexrazoxane) is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications. Totect is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun).