What is the family of pilocarpine?

What is the family of pilocarpine?

Pilocarpine is in the miotics family of medication. It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye.

Which of the following describes pilocarpine?

Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle (when given topically to the eyes) by mainly stimulating muscarinic receptors.

Is pilocarpine an anticholinergic?

Salagen (pilocarpine hydrochloride) is a cholinergic agonist that increases saliva secretion in the mouth used in the treatment of dry mouth.

Is pilocarpine a Miotic?

Direct acting parasympathomimetics. Pilocarpine has been commonly used in the past to lower the intraocular pressure. Pilocarpine is a potent miotic and is available as a solution or gel.

Is pilocarpine a selective?

cholinergic drugs …that is employed therapeutically is pilocarpine, a selective muscarinic-receptor agonist that is used in eyedrops to constrict the pupil and to decrease the intraocular pressure that is raised in the disease glaucoma.

What are the indications of pilocarpine?

Dosage & Indications

• For the treatment of increased intraocular pressure (IOP) in patients with glaucoma or ocular hypertension or for the prevention of increased IOP associated with laser surgery.
• For miosis induction.
• For the treatment of presbyopia.
• For the treatment of xerostomia and/or xerophthalmia†.

What type of alkaloid is pilocarpine?

Pilocarpine (185) is an imidazole-type alkaloid present in jaborandi (Pilocarpus pennatifolius) leaves, which contain about 1% alkaloids with pilocarpine (185) amounting to about half. It has been used for over 100 years for the treatment of chronic open-angle glaucoma and acute angle-closure glaucoma.

Is pilocarpine an agonist?

Pilocarpine is a prototypical drug used to treat glaucoma and dry mouth and is classified as either a full or partial muscarinic agonist.

Is pilocarpine an agonist or antagonist?

Whereas pilocarpine is a full agonist for M1 muscarinic receptor (M1R), we show that it can act as an antagonist for M3R under certain conditions.

Is pilocarpine selective or non selective?

Is pilocarpine a miotic?