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What are the four major functions of the endoplasmic reticulum?
The endoplasmic reticulum (ER) serves important functions particularly in the synthesis, folding, modification, and transport of proteins. Differences in certain physical and functional characteristics distinguish the two types of ER, known as rough ER (RER) and smooth ER (SER).
What is the function of endoplasmic reticulum RER?
rough endoplasmic reticulum (RER), series of connected flattened sacs, part of a continuous membrane organelle within the cytoplasm of eukaryotic cells, that plays a central role in the synthesis of proteins.
What is function Golgi apparatus?
A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.
What diseases are associated with the endoplasmic reticulum?
Endoplasmic reticulum (ER) dysfunction might have an important part to play in a range of neurological disorders, including cerebral ischaemia, sleep apnoea, Alzheimer’s disease, multiple sclerosis, amyotrophic lateral sclerosis, the prion diseases, and familial encephalopathy with neuroserpin inclusion bodies.
What is the rough ER job?
The rough ER, studded with millions of membrane bound ribosomes, is involved with the production, folding, quality control and despatch of some proteins. Smooth ER is largely associated with lipid (fat) manufacture and metabolism and steroid production hormone production. It also has a detoxification function.
What is the function of endoplasmic rectum?
See Article History. Alternative Title: ER. Endoplasmic reticulum (ER), in biology, a continuous membrane system that forms a series of flattened sacs within the cytoplasm of eukaryotic cells and serves multiple functions, being important particularly in the synthesis, folding, modification, and transport of proteins .
What is the role of endoplasmic reticulum in protein synthesis?
Though Smooth Endoplasmic Reticulum (SER) does not take part in protein synthesis unlike Rough Endoplasmic Reticulum (RER), it plays an important role in protein transportation. It regulates the transportation of proteins by acting as a transitional area for vesicles that transfer proteins to various locations.
What does smooth ER produce?
Endoplasmic Reticulum. In liver cells the smooth ER contains enzymes for the detoxification of harmful drugs and metabolic by-products. In the reproductive organs, smooth ER in the cells produces the steroid hormones testosterone and estrogen.