How many cylindrical glass tubes are present in disintegration test apparatus?

How many cylindrical glass tubes are present in disintegration test apparatus?

six cylindrical glass tubes
The basket-rack assembly is rigid and supports six cylindrical glass tubes, 77.5 ± 2.5 mm long, 21.5 mm in internal diameter and with a wall thickness of about 2 mm (Fig.).

Which apparatus is used for disintegration test?

Disintegration Tester is a solid state instrument designed for the accurate estimation of disintegration time of tablets as per IP/USP standards. The instrument is designed to test two batches of six tablets, simultaneously. The unit is extremely useful for pharmaceutical industries.

What is the criteria for disintegration test?

The test is met if all of the dosage units have disintegrated completely. If 1 or 2 dosage units fail to disintegrate, repeat the test on 12 additional dosage units. The test is met if not less than 16 of the total of 18 dosage units tested are disintegrated.

What is the diameter of disintegration test apparatus?

Apparatus. The main part of the apparatus is a rigid basket-rack assembly supporting 6 cylindrical transparent tubes 77.5 ± 2.5 mm long, 21.5 mm in internal diameter, and with a wall thickness of about 2 mm.

What is 5.3 disintegration test?

11. This test is provided to determine whether tablets or capsules disintegrate within the prescribed time. 12. when placed in a liquid medium under the experimental conditions presented below.

What is the use of disc in disintegration test?

When specified in the monograph, cylindrical disks (discs) are employed to aid in the testing of solid dosage forms such as ODTs that tend to float in the immersion media (usually water). The disks help to ensure submersion of the dosage unit and the necessary surface wetting to facilitate disintegration.

What is the limit of disintegration for enteric coated tablets?

uncoated tablets pass the test if each of the six uncoated tablets disintegrates3 in not more that 45 minutes; plain coated tablets pass the test if each of the six plain coated tablets disintegrates in not more than 60 minutes.

What is DT in pharma?

Disintegration time is the time required for a dosage form to break up in to granules of specified size (or smaller) under carefully specified conditions. In other words DT (disintegration time) is measuring the break down of a dosage form and dissolution is measuring the drug being solubilized in the media.

What is principle disintegration?

Complete disintegration is defined as that state in which any residue of the unit, except fragments of insoluble coating or capsule shell, remaining on the screen of the test apparatus or adhering to the lower surface of the disk, if used, is a soft mass having no palpably firm core.

What is the principle of disintegration?

Disintegration testing measures the ability of a tablet to break down into smaller particles or granules to allow the active drug to be absorbed into the body.

What is weight variation test?

In the case of pharmaceutical dosage forms, the weight variation test (also referred to as uniformity of dosage units) is a non-destructive test that compares the individual weights of a sample of tablets with the average weight of the selected sample.