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How do you deal with the side effects of methotrexate?
Managing Methotrexate Side Effects
- Take a folic acid supplement.
- Take methotrexate after meals, which may reduce the risk of stomach upset.
- Use a lower dose.
- Take MTX close to the weekend.
- Consider the side effect profile of other medication you take.
Do side effects of methotrexate go away?
Many patients on methotrexate have few or no side-effects. Among those who do have problems, most side-effects resolve by lowering the dose or, if needed, discontinuation of the drug. But your dose should never be lowered – nor discontinued – without the guidance of your physician.
Why does methotrexate make me feel bad?
Methotrexate blocks some of the actions of folic acid, which can lead to side effects such as mouth sores, abdominal pain, liver problems, hair loss, and anemia.
How long does it take to recover from methotrexate?
In healthy adults, it takes up to 1 week, on average, for most of the methotrexate to be gone from the body. Certain medications and people who have reduced kidney function or a condition that leads to extra body fluid may also clear methotrexate more slowly.
When do methotrexate side effects start?
What are the possible side effects of methotrexate? Methotrexate can cause gastrointestinal upset, fatigue, or even flu-like symptoms in some people. If it occurs, it is usually the day or two after you have taken your methotrexate.
How long does methotrexate make you feel sick?
Although methotrexate is generally very well tolerated, nausea is one of the most common side effects. This tends to occur most frequently 24-48 hours after the weekly dose is administered. There are several strategies to manage this side effect.
How do you stop feeling sick after taking methotrexate?
Some find that splitting the dose eases GI side effects. Take half the pills in the morning and the other half 12 hours later, preferably with food. Ask about anti-nausea medication. For very severe stomach upset, your doctor can prescribe an anti-nausea drug such as ondansetron (Zofran).
Can you eat bananas while taking methotrexate?
Eat mild foods, such as rice, dry toast or crackers, bananas, and applesauce. Avoid spicy foods, other fruits, alcohol, coffee, and dairy products.
When do side effects of methotrexate start?
“The most common side effects are fatigue a day or two after you take methotrexate, which is why I suggest taking it at night,” he says. “Also gastrointestinal issues. Your stool may be loose, or you may feel queasy or nauseated for a day or two after.