What happens if I take amlodipine and grapefruit?

What happens if I take amlodipine and grapefruit?

Results: When amlodipine was coadministered with grapefruit juice, Cmax was 115% and AUC(0-72 h) was 116% compared with water, but tmax was not significantly changed. There were no significant differences in BP and HR between the two treatments.

Is it safe to eat grapefruit while taking blood pressure medicine?

Grapefruit contains compounds that may interfere with how your body absorbs some drugs, including some blood pressure medicines. It can leave too much or too little of the drug in your bloodstream, which may be dangerous.

Can you drink orange juice while taking amlodipine?

Consumer information for this interaction is not currently available. GENERALLY AVOID: Coadministration with orange, apple, or grapefruit juice may significantly decrease the oral bioavailability and renin-inhibiting effect of aliskiren.

How do I stop taking amlodipine?

Do not stop taking amlodipine suddenly. Although no “rebound” effect has been reported, it is better to slowly decrease the dosage over a period of time. Your doctor may advise you to take sublingual nitroglycerin for any break-through angina pain.

Does grapefruit interfere with amlodipine?

Amlodipine also interacts with grapefruit, but in a very small way, not affecting either blood pressure or heart rate, according to a study published in 1996 in the “European Journal of Clinical Pharmacology.”

What are the side effects of 10 mg of amlodipine besylate?

dizziness,drowsiness;

  • feeling tired;
  • stomach pain,nausea; or
  • flushing (warmth,redness,or tingly feeling).
  • Is grapefruit juice a beta blocker?

    Although grapefruit juice interacts with many medications, it does not affect beta blockers. However, because beta blockers can be affected by some foods and over-the-counter medications, if you are taking beta blockers you should talk to your doctor about food and drug interactions. Pink grapefruit juice in a clear cup.