Is Morquio Syndrome Real?

Is Morquio Syndrome Real?

Morquio syndrome is a rare genetic condition that affects a child’s bones and spine, organs, and physical abilities. Children with this condition are missing or don’t produce enough of the enzymes that break down sugar chains naturally produced in the body.

What is another name for Morquio syndrome?

Morquio syndrome, also known as Mucopolysaccharidosis Type IV (MPS IV), is a rare metabolic disorder in which the body cannot process certain types of sugar molecules called glycosaminoglycans (AKA GAGs, or mucopolysaccharides).

Is Morquio syndrome life threatening?

The fact that only one death in this age group was attributed to cardiac failure may also indicate that the cardiovascular complications associated with Morquio syndrome A have yet to become life-threatening in this age group, particularly as cardiac failure is likely to develop secondary to respiratory impairment and …

What disease did Freak the Mighty Have?

Kevin “Freak” Avery is a disabled, blonde-haired boy whom Max becomes best friends with. Kevin has Morquio syndrome, where the outside of his body cannot grow. He walks on crutches and wears a leg brace. He is a genius for his age and size and is cuttingly sarcastic.

What health issues will someone with Morquio syndrome likely face?

The problems tied to Morquio syndrome lead to symptoms such as curved spine (scoliosis), joints that move more than they should (hypermobility), neck that moves more than it should (instability), a large head, short stature, wide teeth, heart and vision problems and a number of other complications.

Who is Maxwell in Freak the Mighty?

Published in 1993, it was followed by the novel Max the Mighty in 1998. The primary characters are friends Maxwell Kane, a large, developmentally disabled, but kind-hearted boy, and Kevin Avery, nicknamed “Freak”, who is physically disabled but very intelligent. Kevin is diagnosed with Morquio syndrome.

Is Morquio syndrome a progressive disease?

Morquio syndrome is a progressive disease, meaning symptoms get worse as a child grows. Morquio syndrome is part of a group of diseases called mucopolysaccharidosis (MPS). Morquio is also known as MPS IV.

What is Morquio-Brailsford syndrome?

Morquio syndrome (referred to as mucopolysaccharidosis IV, MPS IV, Morquio-Brailsford syndrome, or Morquio) is a rare metabolic disorder in which the body cannot process certain types of mucopolysaccharides (long chains of sugar molecules), which the body uses as lubricants and shock absorbers.

What is the difference between Type A and Type B Morquio syndrome?

The two forms are distinguished by the gene product involved; Type A involves a malfunction in the GALNS gene, while Type B involves a malfunction of the GLB1 gene. The treatment for Morquio syndrome consists of prenatal identification and of enzyme replacement therapy.

What is the rate of incidence of Morquio?

The buildup of GAGs in different parts of the body causes symptoms in many different organ systems. In the US, the incidence rate for Morquio is estimated at between 1 in 200,000 and 1 in 300,000 live births.