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How does J147 work?
J147 is a modified version of a molecule (curcumin) found in the curry spice turmeric. In the years since, the researchers have shown that the compound reverses memory deficits, potentiates the production of new brain cells, and slows or reverses Alzheimer’s progression in mice.
What is Alzheimer disease?
Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. In most people with the disease — those with the late-onset type symptoms first appear in their mid-60s.
What is end-stage dementia?
Sometimes called “late stage dementia,” end-stage dementia is the stage in which dementia symptoms become severe to the point where a patient requires help with everyday activities. The person may also have symptoms that indicate that they are near the end of life.
How is the J147 drug developed?
The approach that lead to development of the J147 drug was to screen candidate molecules for anti-aging effects, instead of targeting the amyloid plaques. It is contrary to most other approaches to developing drugs against Alzheimer’s disease that target the plaque deposits in the brain.
What is J147 (cad-031)?
Basics Of J-147. Basically, J147 (CAD-031) is a Curcumin and Cyclohexyl-Bisphenol A (CBA) derivative that is a potent neurogenic and neuroprotective drug.
What is j-147 used for?
Basics Of J-147. Basically, J147 (CAD-031) is a Curcumin and Cyclohexyl-Bisphenol A (CBA) derivative that is a potent neurogenic and neuroprotective drug. It was developed for the use of treating neurodegenerative conditions associated with aging. Curcumin is a polyphenol and the active component of Turmeric and Ginger.
How does J147 improve memory?
Unlike the current drugs approved for Alzheimer’s Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term treatment. In this post, we will discuss how the curcumin derivative J147 improves memory and I’ll explain a very powerful alternative way to get its benefits.