What are the organic and inorganic components of bone matrix?

What are the organic and inorganic components of bone matrix?

Bone matrix (also known as osteoid) consists of about 33% organic matter (mostly Type I collagen) and 67% inorganic matter (calcium phosphate, mostly hydroxyapatite crystals).

What is inorganic matrix of bone?

The inorganic matrix of bone consists of a calcium hydroxyapatite, which is in a crystalline structure. This serves to: 99% of the body’s calcium, 85% of its phosphorous, 65% of its sodium and magnesium.

What is the bone matrix made up of?

Bone matrix The hardness and rigidity of bone is due to the presence of mineral salt in the osteoid matrix, which is a crystalline complex of calcium and phosphate (hydroxyapatite). Calcified bone contains about 25% organic matrix (2-5% of which are cells), 5% water and 70% inorganic mineral (hydroxyapatite).

What are the inorganic compounds that make up bone?

In addition to calcium, phosphorous, water, and fluoride, the inorganic parts of bone also contain sodium, potassium, carbonate, and magnesium. Although these molecules do not form their own crystals, they are bound to hydroxyapatite crystals within bone mineral.

What are the components of the organic bone matrix and what is its function?

Organic and Inorganic Combination The incorporation of hydroxyapatite within the collagen fibers contributes to the overall compressive strength of bone. Within the bone matrix, the minerals, water, collagens, and proteoglycans function together to provide strength in tension and compression.

How is the bone matrix formed?

Bone matrix is synthesized by a layer of osteoblasts on the bone surface (Figs. 1-22 and 1-23). The osteoblasts are mesenchymal in origin and characterized by their abundant endoplasmic reticulum and their production of the enzyme alkaline phosphatase.

What are the organic and inorganic components of bone quizlet?

As described above, by volume, bone consists of 40% inorganic component (hydroxyapatite), 25% water and 35% organic component (proteins) [1,2,12].

How are the organic and inorganic components of bone integrated?

Organic and Inorganic Combination Mineralization of the bone matrix occurs when calcium, phosphate, and water from the extracellular fluids combine to form insoluble hydroxyapatite. The incorporation of hydroxyapatite within the collagen fibers contributes to the overall compressive strength of bone.

Which is part of the inorganic matter that makes up the matrix of bone quizlet?

The inorganic portion of the bone matrix is made up of salt crystals that are primarily calcium phosphate, Ca3(PO4)2. Calcium phosphate and calcium hydroxide interact to form crystals of hydroxyapatite, which is Ca10(PO4)6(OH)2.

What is the function of the organic matrix in bone?

An organic matrix of a bone is 34%, while 90% of the bone protein has a triple helical structure with less non-collagenous proteins. In addition to that, an inorganic and natural connection in the bone matrix enhances bone resorption, which occurs in the intracellular and extracellular phase.

What are the inorganic components of bone?

The organic component of the bone matrix includes the collagen and ground substance whereas the inorganic component is the inorganic bone salts, mainly the hydroxyapatite. The collagen and ground substance form approximately 25% of the bone mass. Collagen, though, is the predominant organic component.

What is the function of bone matrix?

Bone Biomarkers. Bone matrix is comprised of nearly 90% Type 1 collagen. Serum concentration of the precursor molecule, procollagen, is elevated in the setting of early bone formation and osteoblast activity. Similarly, the degradation products of Type 1 collagen can be used as markers of bone resorption.

What is organic bone matrix?

The bone matrix is that part of the bone tissue and forms most of the mass of the bone. It is comprised of organic and inorganic substances. The organic component of the bone matrix includes the collagen and ground substance whereas the inorganic component is the inorganic bone salts, mainly the hydroxyapatite.