Admin Table of Contents
- 1 What is the purpose of adding NaOH to the solution of acetylsalicylic acid?
- 2 Why must ethanol be added to the water prior to doing the titration?
- 3 Why is ethanol added to the solution of aspirin?
- 4 Why is the synthesized aspirin in the laboratory Cannot be used for commercial and pharmaceutical purposes?
- 5 What is the limiting reagent for synthesis of aspirin?
- 6 What happens when you add FECL to an aspirin sample?
- 7 How do you dissolve aspirin in ethanol?
What is the purpose of adding NaOH to the solution of acetylsalicylic acid?
To determine the amount of aspirin (acetylsalicylic acid) in a sample, the precise volume and concentration of the NaOH, and the overall reaction, must be known. The NaOH serves as a secondary standard, because its concentration can change over time.
Why must ethanol be added to the water prior to doing the titration?
water — the ethanol helps the aspirin dissolve. Note that an aspirin tablet contains other compounds in addition to aspirin. Some of these are not very soluble. Your solution will be cloudy due to insoluble components of the tablet.)
What happens when you add HCl to sodium Acetylsalicylate?
If 6M HCl is added to the solution of sodium acetylsalicylate, it forms aspirin.
Why is aspirin soluble in sodium hydroxide?
Aspirin would be slightly soluble in NaOH because the carboxylic acid group would be deprotonated making it negatively charged.
Why is ethanol added to the solution of aspirin?
(Aspirin is not very soluble in water — the ethanol helps the aspirin dissolve. Note that an aspirin tablet contains other compounds in addition to aspirin. Some of these are not very soluble. Your solution will be cloudy due to insoluble components of the tablet.)
Why is the synthesized aspirin in the laboratory Cannot be used for commercial and pharmaceutical purposes?
In this laboratory activity you will synthesize aspirin, a derivative of salicylic acid. Salicylic acid and its derivatives are antipyretics. Salicylic acid itself is not used for these purposes because it has an irritating effect on the stomach. The most common salicylate used in medicine today is aspirin.
What is the purpose of synthesis of aspirin?
The purpose of this lab was to synthesize Aspirin and measure the synthesized Aspirin’s purity. By calculating the theoretical yield based on the original amount of Salicylic acid, one could determine the actual yield percentage of the reaction.
What is the purpose of the synthesis of aspirin lab?
What is the limiting reagent for synthesis of aspirin?
The acetic acid which is water soluble, can be separated from the aspirin by filtration. The salicyclic acid will be the limiting reagent.
What happens when you add FECL to an aspirin sample?
The collected aspirin will be tested for its purity using FeCl 3 (aq). Iron (III) ion reacts with phenols to form a purple complex. Salicylic acid contains a phenol group, but acetylsalicylic acid does not. Therefore, if you add FeCl to an aspirin sample and you see 3
What happens when you mix aspirin with acetylsalicylic acid?
The acetylsalicylic acid will recrystallize, and the solid impurities (unreacted salicylic acid) should remain dissolved in the solution. The solid aspirin will again be collected using vacuum filtration and tested for purity. This aspirin should be more pure than the original aspirin.
What happens during esterification of aspirin?
When the esterification reaction is complete, water will be added to the mixture. This will cause the precipitation of the acetylsalicylic acid and will react with any remaining acetic anhydride. The solid aspirin will be collected using vacuum filtration.
How do you dissolve aspirin in ethanol?
To each flask, add 20 mL of ethanol (measure by graduated cylinder) and three drops of phenolphthalein indicator. Swirl gently to dissolve. (Aspirin is not very soluble in water — the ethanol helps the aspirin dissolve. Note that an aspirin tablet contains other compounds in addition to aspirin.