When is rectal administration the preferred route of administration?

When is rectal administration the preferred route of administration?

Parenteral and rectal routes of administration are preferred when quick therapeutic response is required. Rectally administered drugs are found to achieve better plasma levels and therapeutic effectiveness when compared with orally or intramuscularly administered drugs of similar dose [66].

How do you take rectal medicine?

Using your finger, gently insert the suppository well up into the rectum, pointed end first. After insertion, stay in position for 15 to 20 minutes if possible until you feel a strong urge to have a bowel movement. This product does not need to melt completely to produce an effect.

How are rectal suppositories administered?

Insert the suppository into the rectum, narrow end first. Gently but firmly, push the suppository past the sphincter. The sphincter is the muscular opening of the rectum. For adults, push it in one inch.

What type of drug delivery is a rectal suppository?

Suppositories are a medicated solid dosage form intended for insertion into the body orifices. Suppositories and creams are the two main modes of administration of drugs through the rectum. They are used to deliver both systemically acting and locally-acting medications.

Why is rectal Drug Administration recommended?

Rectal absorption results in more of the drug reaching the systemic circulation with less alteration on route. As well as being a more effective route for delivering medication, rectal administration also reduces side-effects of some drugs, such as gastric irritation, nausea and vomiting (Tortora and Derrickson, 2008).

What is suppository form?

A suppository is a dosage form used to deliver medications by insertion into a body orifice where it dissolves or melts to exert local or systemic effects.

What are the two types of rectal drugs?

Medication intended for rectal administration often comes in the form of a suppository or an enema. Suppositories (Fig 1a attached) are small, torpedo-shaped pellets that melt at body temperature, whereas enemas (Fig 1b, attached) are substances in liquid form designed for rectal administration.

What are the types of suppositories?

There are three types of suppositories:

• Rectal suppositories. Rectal suppositories go in the rectum or anus.
• Vaginal suppositories. People may insert vaginal suppositories into the vagina to treat:
• Urethral suppositories. Men may use a type of urethral suppository to treat erection problems in rare cases.

What are the types of rectal drugs?

Table 1

What are the different types of suppositories?

What are suppositories and its types?

There are three types of suppositories, each to insert into a different sections: Rectal suppositories into the rectum, vaginal suppositories into the vagina, and urethral suppositories into the urethra of a male.

What is rectal administration of medication?

Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum’s blood vessels, and flow into the body’s circulatory system, which distributes the drug to the body’s organs and bodily systems. A drug that is administered rectally will in…

How do you administer internal rectal medicated cream?

Administration of internal rectal medicated cream or ointment requires placement of the applicator’s lubricated tip at the rectal opening, gently pushing the applicator into the rectal opening about 3 inches (7.5 cm) for an adult (or as indicated on the applicator’s directions).

What is the difference between oral and rectal route of administration?

A drug that is administered rectally will in general (depending on the drug) have a faster onset, higher bioavailability, shorter peak, and shorter duration than oral administration. Another advantage of administering a drug rectally, is that it tends to produce less nausea compared to the oral route…

What are the drawbacks of rectal Drug Administration?

Drawbacks of rectal drug administration include the interruption of absorption by defaecation and lack of patient acceptability.