Admin Table of Contents
What is eosinophilic cellulitis?
Wells syndrome (eosinophilic cellulitis) is an uncommon condition of unknown etiology. The presentation usually involves a mildly pruritic or tender cellulitis-like eruption with typical histologic features characterized by edema, flame figures, and a marked infiltrate of eosinophils in the dermis.
How do you treat Wells syndrome?
The skin symptoms associated with wells syndrome are typically treated with oral or topical corticosteroids such as Prednisone . Other medications that may be used to treat this condition include antifungal drugs, antibiotics , immunosuppressants, and/or antihistamines (H1 receptor antagonists).
What is eosinophilic annular erythema?
INTRODUCTION. Eosinophilic annular erythema (EAE) is an uncommon benign acute eosinophilic dermatosis of unknown etiology, originally described in children. 1,2. EAE is clinically characterized by recurrent annular, erythematous-edematous, pruritic lesions with a centrifugal growth pattern.
What is flame figure?
Flame figures represent dermal collagen fibers coated with eosinophilic granules, first described in eosinophilic cellulitis (Wells syndrome).
What do eosinophils do?
Eosinophils are a type of white blood cell. They help fight off infections and play a role in your body’s immune response. They can also build up and cause inflammation.
What drugs can cause eosinophilia?
Drug-induced eosinophilia
| Drug | Type of reaction |
|---|---|
| Tryptophan | Multisystem; musculosketetal and dermal problems common |
| Anticonvulsants, eg, phenytoin, carbamazepine and phenobarbitone | Multisystem; dermal, liver, cardiac and pulmonary complications reported |
| NSAIDs | Usually pulmonary complications |
| Gold | Usually dermal complications |
Can eosinophilia cause swelling?
What are eosinophilic fasciitis symptoms and signs? Eosinophilic fasciitis causes inflammation of the tissues beneath the skin as well as sometimes in the skin. This leads to symptoms of swelling, stiffness, warmth, and pain of the involved area.
What autoimmune disease causes cellulitis?
An autoimmune disease — such as lupus or rheumatoid arthritis — can also weaken the immune system. This not only makes you vulnerable to cellulitis, but also to other infections, such colds and the flu.
What is erythema annulare Centrifugum?
Erythema annulare centrifugum (EAC) is an annular, erythematous lesion that appears as an urticaria-like papule and enlarges centrifugally, then clears centrally. A fine scale is sometimes present inside the advancing edge, known as a trailing scale.